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health:cancer [2019/08/13 16:45] marcos [Head and Neck Cancer] |
health:cancer [2019/10/26 20:54] (current) marcos [Mutational Theory of Cancer] |
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These very few mutated cells may in some way be able to out-compete neighboring cells. While these cells could have advantage over neighboring cells in terms of competitive survival, they may not necessarily be the most effective towards the overall health of the organism. This is an aspect of the aging process. In the case of cancer, the mutated cell proliferation will likely cause an organism's death. | These very few mutated cells may in some way be able to out-compete neighboring cells. While these cells could have advantage over neighboring cells in terms of competitive survival, they may not necessarily be the most effective towards the overall health of the organism. This is an aspect of the aging process. In the case of cancer, the mutated cell proliferation will likely cause an organism's death. | ||
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+ | Mutated cells can happen in different stages of life, and results in [[https://dx.doi.org/10.1016%2Fj.gde.2016.12.002 |clonal mosaicism]], including where different regions of the body have differing genomes. | ||
The imperfections in the machinery for DNA maintenance and DNA replication, could be more exact and fault tolerant. However, a certain level of mutation is beneficial for the survival of a species in a changing environment. Cancer and aging are products of the evolutionary process. | The imperfections in the machinery for DNA maintenance and DNA replication, could be more exact and fault tolerant. However, a certain level of mutation is beneficial for the survival of a species in a changing environment. Cancer and aging are products of the evolutionary process. |