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--- health:antioxidants [2019/07/18 17:16]
marcos
+++ health:antioxidants [2020/07/13 04:48] (current)
marcos
@@ Line 1: / Line 1: @@
-===== Antioxidants =====
+{{htmlmetatags>
+metatag-description=(Searching through scientific literature for antioxidants to optimize health.)
+metatag-keywords=(antioxidants, antioxidants benefits, antioxidant supplements, antioxidant (medical treatment), how antioxidants work, what do antioxidants do, antioxidant and food, antioxidants and free radicals, what is an antioxidant, oxidative stress, anti-oxidant, CoQ10, Vitamin C, Selenium, Polyphenols, Melatonin)
+}}
+~~META:
+title = Which Antioxidants Are Worth Supplementing?
+~~
+// Searching through scientific literature for antioxidants to optimize health. //
+====== Antioxidants ======
 [[https://en.wikipedia.org/wiki/Antioxidant |Antioxidants]] prevent cell damage from free radicals.  Free radicals are unstable molecules created in the natural process of metabolism, and at an accelerated rate during exercise.  Free radicals also form due to exposure from environmental sources such as cigarette smoke, air pollution or sunlight.
-However, when it comes to antioxidants, they are not just purely beneficial:\\
+===== Which Antioxidants are Worth Supplementing? =====
+When it comes to antioxidants, they are not just purely beneficial:\\
+https://www.dovepress.com/oxidative-stress-aging-and-diseases-peer-reviewed-fulltext-article-CIA\\
 https://www.consumerreports.org/cro/2013/03/antioxidants-more-is-not-always-better/index.htm\\
 https://joshmitteldorf.scienceblog.com/2012/11/19/anti-oxidants-a-disappointment-or-worse\\
-(these need to be replaced with systematic reviews or a group of individual peer-reviewed studies)
-Vitamin C, has overall good health effects [[https://examine.com/supplements/vitamin-c | 1]][[https://www.selfhacked.com/blog/need-know-vitamin-c-32-science-based-health-benefits | 2]] when supplemented above the [[https://en.wikipedia.org/wiki/Dietary_Reference_Intake | Dietary Reference Intake]], but it reduces performance gains from exercising:\\
+The problem is, that you can't just take tons of antioxidants, because some processes requires the presence of the reactive oxidant species in order to function.  In other words, human body has evolved to include reactive oxygen species.
+For example, growth is triggered by the presence of ROS, such as those that accumulate after heavy exercise. ROS signals the need for muscle growth and for additional mitochondria.  Antioxidants consumed in large quantity can block this growth.
+There are many antioxidants, but ones that have been studied for supplementation include Vitamins, CoQ10, Polyphenols, Selenium, and Melatonin.
+__**Vitamin C**__ supplementation can have overall good health effects ((https://examine.com/supplements/vitamin-c)) ((https://www.selfhacked.com/blog/need-know-vitamin-c-32-science-based-health-benefits)) when supplemented above the [[https://en.wikipedia.org/wiki/Dietary_Reference_Intake | Dietary Reference Intake]], but it reduces performance gains from exercising:\\
 https://academic.oup.com/ajcn/article/87/1/142/4633311\\
+https://www.ncbi.nlm.nih.gov/pubmed/19433800\\
 https://www.ncbi.nlm.nih.gov/pubmed/22777327
-The [[https://en.wikipedia.org/wiki/National_Center_for_Complementary_and_Integrative_Health |NCCIH]] [[https://nccih.nih.gov/health/antioxidants/introduction.htm |recommends the following]]:
+Low levels of __**CoQ10**__ has been associated with disease.  Oral administration of CoQ10 has been frequently administered in treatment resulting in mild to significant symptomatic improvement. ((Garrido-Maraver J, Cordero MD, Oropesa-Ávila M, et al. Coenzyme q10 therapy. Mol Syndromol. 2014;5(3–4):187–197.)) ((https://examine.com/supplements/coenzyme-q10))
-  * Scientists have researched anti-oxidant supplements to check whether they help to reduce diseases like cardiovascular disease, cancer, and cataracts. Results indicate that antioxidants didn’t lessen the risk of developing these.
-  * High doses of antioxidant supplements can cause unpredictable harm.  When taken in high doses, anti-oxidants can act as pro-oxidants, increasing production of free-radicals.  High doses of beta carotene can increase the risk of lung cancer in smokers.  Use of high-doses of vitamin E supplements upsurge the risk of hemorrhagic stroke and prostate cancer.
-  * Certain antioxidant supplements are known to interact with some medicines.  Vitamin E can increase the risk of bleeding in people who use anticoagulant drugs (blood thinners).
-**Antioxidants and Aging**
+__**Selenium**__ dosage is sufficient through a healthy diet.  Not enough or too high a dosage both lead to disease.  An optimal dosage is still being researched. ((Sanmartin C, Plano D, Font M, Palop JA. Selenium and clinical trials: new therapeutic evidence for multiple diseases. Curr Med Chem. 2011; 18(30):4635–4650.))
-Humans can live longer under certain types of stress (an effect of hormesis).  When our body is stressed it upsurges its defenses.  This can be seen with exercise, with starvation, and with many toxins (what toxins? please specify).
+===== Antioxidants and Aging =====
-At an older age, the body isn't doing it's best to protect itself from damage.  It willfully allows the damage to accumulate.  Defensive programming is turned off and decay is allowed to overtake us.
+At an older age, the body isn't doing it's best to protect itself from damage.  It willfully allows the damage to accumulate.  Defensive programming is turned off and decay is allowed to overtake us. ((http://www.phdish.com/blog/antioxidants-and-aging)) ((https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685276))
-[[http://www.phdish.com/blog/antioxidants-and-aging |1]]
-[[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685276 |2]]
 --- //[[user:humaira|Humaira Sarfraz]] 2019/07/15 //\\
 --- //[[user:marcos|Marcos Reyes]] 2019/07/15 //
+\\

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